Alexander Bernhardt, MD, from University Heart and Vascular Center in Hamburg, Germany, discusses the use of Impella® in patients suffering from post-cardiotomy cardiogenic shock (PCCS). He describes how Impella support can optimize patients pre-operatively, be used intraoperatively in a preventive setting, or be used post-operatively to treat patients once post-cardiotomy failure occurs. He discusses IMPACT EU, a prospective, multicenter trial examining use of Impella 5.5® for improving functional status and quality of life in high-risk cardiac surgery patients with severe LV dysfunction. He concludes with a case study from his center.