Hursh Naik, MD, with Riyaz Sumar, MD, and Kevin Brady, MD, perform a case of combined multivessel high-risk PCI with transcatheter aortic valve replacement (TAVR) in a 75-year-old patient with low ejection fraction and severe aortic stenosis. Seth Bilazarian, MD, with panelists Raj Tayal, MD, and Thom Dahle, MD, offers thoughts on combining PCI with TAVR, especially during the COVID era. The case was performed at St. Joseph’s Hospital in Phoenix, Arizona.